How BONIVA Works

Information for Healthcare Professionals

Once-monthly BONIVA is a bisphosphonate treatment for postmenopausal osteoporosis.

BONIVA is clinically proven to maintain—and actually increase—bone density. It is the only osteoporosis medicine to do this with just one tablet a month.

You get continuous bone protection throughout the month with just one BONIVA Tablet, because BONIVA binds with and stays in bones. BONIVA is designed to last the entire month.

And for those who have difficulty with oral dosing requirements, there is BONIVA Injection.

Ask your healthcare provider if BONIVA is right for you,and find out how to get one month free.

Read full Prescribing Information.

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BONIVA is a prescription medicine for the management of postmenopausal osteoporosis.

Important Safety Information (Tablets)

You should not take BONIVA if you have low blood calcium, cannot sit or stand for at least 60 minutes, have severe kidney disease, or are allergic to BONIVA. Stop taking BONIVA and tell your healthcare provider if you experience difficult or painful swallowing, chest pain, or severe or continuing heartburn, as these may be signs of serious upper digestive problems. Follow the dosing instructions for the once-monthly BONIVA 150 mg Tablet carefully to lower the chance of these events occurring. Side effects are generally mild or moderate and may include diarrhea, pain in the arms or legs, or upset stomach. If you develop severe bone, joint, and/or muscle pain, contact your healthcare provider. Your healthcare provider may also recommend a calcium and vitamin D supplement.

Important Safety Information (Injection)
BONIVA Injection is a prescription medicine used to treat postmenopausal osteoporosis. BONIVA Injection must be administered intravenously (IV) only by a healthcare professional. Do NOT administer BONIVA Injection to yourself. Patients with severe kidney problems or who are allergic to BONIVA should not receive BONIVA Injection. You should have a blood test to check your kidneys prior to each injection of BONIVA. Your doctor must correct low blood calcium and vitamin D levels before starting BONIVA Injection therapy. You must also take calcium and vitamin D supplements while receiving BONIVA Injection therapy.

Side effects are usually mild and of brief duration. The most common side effects with BONIVA Injection are bone, muscle, or joint pains, flu-like illness and headache. Flu-like symptoms usually occur only after the first injection of BONIVA. If you develop severe bone, joint, and/or muscle pain, contact your healthcare provider.

GlaxoSmithKline